Teva Pharmaceutical Industries launched its Adasuve inhaled powder for the treatment of agitation associated with schizophrenia and bipolar I disorder in the U.S. The drug is the first of its kind with this delivery system, which uses Alexza Pharmaceuticals' Staccato device for absorption in the lungs.
In the biotech and pharma industries, drug delivery is a crucial aspect of research and development. Finding new ways to deliver old drugs, ways to make a new drug more efficient or ways that make a patient's life easier could all give a company a leg up on its competitors. But with the amount of R&D time and money needed to innovate in the field, it's often left to smaller specialty companies--and their partnerships with Big Biotech and Big Pharma--to bring these new techniques to the market. Check out the report >>
Any industry that's undergoing as much change as biopharma is always looking for leadership. Old marketing practices are being blown apart, R&D is being subjected to emergency surgery, drug prices surge ever higher, spurring a growing backlash from payers.
In this constantly shifting panorama you'll find a group of executives who are forging new paths for others to follow. This year, the third for Fierce, we present the men and women whose influence is being felt across the industry.
Influence, of course, isn't always a force for good. But it can be. To be truly influential in an industry, you need to be able to persuasively explain new methods that can exert a powerful hold on colleagues in the same global field. Some of this year's group have excelled in that regard.
We hope you enjoy this year's report. And please offer any suggestions you may have for next year's project on the influentials.
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AstraZeneca won U.S. approval of its Bydureon pen for once-weekly treatment of Type 2 diabetes. The pen will be the first of its kind to hit the market. The prefilled, single-use pen injector delivers microspheres that house exenatide, which is slowly released for better glycemic control.
A study of a vaginal ring for the prevention of HIV came back with mixed results. The ring, which delivers two drugs, was safe for 28 days, but only one of the antiretroviral drugs was effective in protecting against the virus.
Texas oral drug delivery specialist Neos Therapeutics pulled in $15.5 million in a Series C round of financing to help propel its line of ADHD controlled-release treatments to the market.
Research in drug delivery is shifting further and further to the nano scale, and while nanotechnology still hovers for the most part just short of the clinical stage, new techniques in manufacturing the particles are crucial to bringing them to the next step.
A research team published in Nature's open-access journal Scientific Reports a proof-of-concept study for a drug delivery system using a tattoo to treat cutaneous leishmaniasis, a potentially deadly skin disease spread by bites from sandflies.
To tackle difficult-to-treat drug-resistant ovarian cancer, researchers at Tel Aviv University have developed nanoparticles designed to accumulate in clusters in tumors to deliver chemotherapy, increasing efficacy and reducing side effects.
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