Researchers at the Institute of General Physics at the Russian Academy of Sciences and the Moscow Institute of Physics and Technology said their advancement in biocomputing using nanoparticles is a step towards creating drug-delivering nanorobots.
The FDA's Pulmonary-Allergy Drugs Advisory Committee (PADAC) voted 10-3 to recommend approval of Boehringer Ingelheim's mist formulation of its dry-powder inhalable treatment for chronic obstructive pulmonary disease (COPD). If approved, the new product, Spiriva Respimat, would give clinicians an alternative to the company's FDA-approved tiotropium bromide inhalable dry powder, the Spiriva HandiHaler.
Any industry that's undergoing as much change as biopharma is always looking for leadership. Old marketing practices are being blown apart, R&D is being subjected to emergency surgery, drug prices surge ever higher, spurring a growing backlash from payers.
In this constantly shifting panorama you'll find a group of executives who are forging new paths for others to follow. This year, the third for Fierce, we present the men and women whose influence is being felt across the industry.
Influence, of course, isn't always a force for good. But it can be. To be truly influential in an industry, you need to be able to persuasively explain new methods that can exert a powerful hold on colleagues in the same global field. Some of this year's group have excelled in that regard.
We hope you enjoy this year's report. And please offer any suggestions you may have for next year's project on the influentials.
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Columbia University scientists showed that it is possible to control the size of the blood-brain barrier (BBB) opening by varying the pressure of an ultrasound beam, a discovery that could herald major breakthroughs in the treatment of neurological diseases. Read more >>
Engineers and cell biologists have long used pulsed lasers to stimulate cells for gene transfection, drug injection or the regulation of gene expression. Now, Japanese scientists uncovered a new, potentially less-expensive method of delivering drugs and manipulating genes of individual cells by pairing nanosecond laser energy with carbon nanotubes.
Alnylam Pharmaceuticals received a Notice of Allowance from the U.S. Patents and Trademarks Office for an application granting the company new claims to RNA interference (RNAi) medicines.
Researchers successfully delivered the immunosuppressant tacrolimus in a self-assembled hydrogel, enabling localized therapy in patients receiving a tissue graft transplant of the leg, hand or face.
Arrowhead Research reported on Aug. 12 that patients in its Phase II clinical trial of the ARC-520 RNA interference candidate for hepatitis B had a "similar" knockdown to those reported in primate studies. The stock price fell at the very end of the trading day to close at $12.00 from an opening-day price of $13.00.
A bioengineering professor says he has developed nanoparticles that can carry cancer-fighting insect toxins directly to tumors, sparing the rest of the body from nasty side effects, including damage to the heart, bleeding underneath the skin and unwanted clotting.
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Biotech Otologic Pharmaceuticals has chosen North Carolina's PharPoint Research to run an early trial of its lead candidate, a treatment for hearing loss.
The U.S. Food and Drug Administration has picked up the pace on novel medical device approvals, but this year still may not hit levels seen in 2011 and 2012. During the first six months of 2014, the agency granted 17 premarket approvals, way up from 23 for the entirety of 2013.