News

Study: Patients don't know how to use drug delivery devices

The evidence is clear: Patients don't properly use drug delivery devices like inhalers or epinephrine autoinjectors--such as Mylan's EpiPen.

Molecular 'hats' disguise peptides until activated with UV light at a target

Researchers have found a way to sneak peptides past the immune system by fitting them with cages that cover binding sites on the proteins like a hat. These prevent the binding sites from revealing the peptides' true nature as something from the outside.

Sanofi's newly approved intradermal quadrivalent Fluzone forgoes the shot

The FDA approved Sanofi's Fluzone Intradermal Quadrivalent in adults age 18 through 64.

Researchers form startup to commercialize drug delivering magnets

Researchers at the University of Maryland and Bethesda, MD-based Weinberg Medical Physics have created a startup called Iron Focus Medical that attempts to build on their prior research to commercialize a novel drug delivery system.

MIT spinoff Microchips finishes development of its birth control, osteoporosis implant

Microchips Biotech says it's ready to send its delivery technology out into the world, this week announcing it has completed development and clinical demonstration of the drug-delivering implant.

RNAi specialist Alnylam to focus on three therapeutic areas

Saying it is on track to exceed its goal of having 5 key products in clinical development through 2015, Alnylam recently announced that it intends to focus on three strategic therapeutic areas, or what it dubs "STArs," as it races to commercialize its first candidate delivered using the RNAi pathway and reassure sometimes antsy investors.

ProNAi reports positive PhII lymphoma results for DNAi drug using Marina's delivery tech

ProNAi Therapeutics, a licensee of RNAi specialist Marina Biotech, reported positive results from its so-called DNAi-based candidate PNT2258 for non-Hodgkin lymphoma.

NC State team creates 3-D printer for nanoparticles that offers low-cost production

Because nanoparticles are so different in scale from other drugs on the market, drugmakers will need a way to make them in bulk and at a low cost, though still highly specific in form and function. To that end, researchers have developed a technique for making 3-D structures at the nanoscale, offering repeatable production that is also relatively inexpensive.

Insys collects gastric cancer orphan designation for liposome-trapped paclitaxel

Insys Therapeutics, a combination drug developer and delivery specialist, won an orphan designation from the FDA for a gastric cancer treatment that delivers paclitaxel trapped in liposomes to make the common cancer drug more soluble and less toxic.

3-D vaccine triggers immune response against cancer and infections

Researchers at Harvard University have demonstrated that a nonsurgical injection of programmable biomaterial can assemble in vivo into a 3-D structure to attack cancer cells and help to prevent other infectious diseases such as HIV.

Unilife signs supply agreement for Depot-ject delivery system

Developer and supplier of drug delivery systems Unilife announced last week the signing of a worldwide, 10-year commercial supply agreement with a global pharmaceutical company for the use of its Depot-ject with an ocular injection therapy.

Oramed raises funds for clinical development programs through stock sale

Oramed Pharmaceuticals announced last week that the company received $5 million through a stock sale and agreement with Guangxi Wuzhou Pharmaceutical, which purchased 696,378 restricted shares of Oramed stock at $7.18 per share.

Material used in paints, adhesives can be tailored for drug delivery

Researchers at the University of Illinois at Urbana-Champaign have developed a hydrolyzable polymer that can be used as a drug delivery material.

DBV's peanut allergy patch tests well, boosting its market value to almost $1B

Over the past few years, France's DBV Technologies has been financing its food allergy patch, and a new study showing that the patch helps children tolerate more peanuts has boosted the market value to the tune of $1 billion, according to a report from Bloomberg.

Valerion teams up with Catalent to develop orphan drug delivery tech

Catalent has signed on with Concord, MA-based Valerion Therapeutics to help develop delivery technology for the company's line of orphan genetic treatments.

Recipharm purchases Flamel facility with delivery partnership

Recipharm has purchased a manufacturing facility from Flamel Technologies in Pessac, France, for $13.2 million. The move is part of an effort to incorporate drug delivery technologies into its contract development business.

U.S. Army deploys a novel topical antiseptic to fight Ebola

Microdermis' antiseptic skin product Provodine--which incorporates a novel dermal delivery system--has been adopted by the U.S. Army and will be used in West Africa against ebolavirus.

NIH grants $20M to develop an intravaginal ring to prevent HIV

The National Institutes of Health recently awarded $20 million to a collaboration of researchers led by the Oak Crest Institute of Science to develop a novel intravaginal ring designed to prevent the spread of sexually transmitted HIV in women by delivering powerful combinations of antiretroviral drugs.

RNAi specialist Arrowhead reports loss of $58.7M in FY 2014

Arrowhead Research reported a net loss of $58.7 million in fiscal year 2014, up from $31.7 million in FY 2013.

Singapore team combines cancer drugs, diagnostics in one biomarker nanoparticle

Combining diagnostics and drug delivery is an ideal progression to improve the effectiveness and speed of treatment and a way to make drugs "smarter." To make one of these two-in-one systems, Singapore-based researchers developed a new biomarker that lights up to locate tumors and releases cancer drugs at the same time.