News

Arrowhead updates TheStreet on clinical trial results of RNAi candidate for hepatitis B

Arrowhead Research reported on Aug. 12 that patients in its Phase II clinical trial of the ARC-520 RNA interference candidate for hepatitis B had a "similar" knockdown to those reported in primate studies. The stock price fell at the very end of the trading day to close at $12.00 from an opening-day price of $13.00.

Sharp rise in opioid abuse may benefit drug delivery contenders

The contenders to develop new methods of tackling the problem of opioid addiction should receive a boost from a new study by the federal Agency for Healthcare Research & Quality, which found that the overuse of pain medications has resulted in a 5% average annual increase in adult hospital stays between 1993 and 2012.

Can insect venom be harnessed to fight cancer?

A bioengineering professor says he has developed nanoparticles that can carry cancer-fighting insect toxins directly to tumors, sparing the rest of the body from nasty side effects, including damage to the heart, bleeding underneath the skin and unwanted clotting.

Medicated electrospun fabric offers alternative delivery method for HIV-preventing drugs

Researchers at the University of Washington have developed a medicated, electrospun fabric that could prevent HIV infections in women.

pH-sensing capsules that deliver optimal quantity of insulin under development

Researchers say they successfully tested in mice a molecular implant that contains gene-based mechanisms for delivering insulin based on feedback from an associated pH biosensor. By maintaining a healthy pH level between 7.35 and 7.45, the therapy, consisting of different genes and proteins, would prevent potentially fatal metabolic shock (ketoacidosis) in diabetics. 

Oraya receives NIH grant to study use of its novel eye radiation tech against cancer

Ophthalmology company Oraya Therapeutics will collaborate with researchers from Boston's Dana-Farber Cancer Institute to study applications of its novel radiation therapy against cancer when used in conjunction with gold nanoparticles.

BioDelivery Sciences International to add 80 patients to clinical trial of Clonidine Topical Gel

BioDelivery Sciences International announced today that it will add about 80 patients to its Phase III pivotal trial of Clonidine Topical Gel for the treatment of painful diabetic neuropathy.

BD launches AutoShield Duo pen for diabetics

Becton, Dickinson and Company today announced that its BD AutoShield Duo pen for the delivery of insulin and diabetes drugs is now available in retail pharmacies. 

Thin and strong, graphene sheets form spheres spontaneously for drug release

Graphene is one of the thinnest and strongest known materials and has been used in drug delivery before. But the Nobel Prize-winning material could get another lease on life with a new discovery from Monash University in Australia that could make graphene an important drug release component.

Carnegie Mellon team creates self-assembling nanofibers for shaped delivery vehicles

Polymer nanomaterials are crucial for many types of drug delivery applications, offering the flexibility and durability needed to engineer specific shapes and sizes for particular delivery solutions. Now, at Carnegie Mellon, researchers have developed a new technique for creating self-assembling fibers for this purpose, taking a cue from the natural fibers in living cells.

Biodegradable film strip enabling 14 months of drug delivery prototyped by MIT team

A team of MIT researchers successfully tested a thin-film drug delivery system enabling steady, sustained release of medication for about 14 months, a scientific advancement with major commercial implications. 

Stentys ditches bare metal stent trial as customers move to drug-eluting versions

Stentys announced that it is discontinuing enrollment of its Apposition V trial for its bare metal stent and focusing its resources and money on its next-generation sirolimus-eluting stent featuring a new delivery catheter.

Nature-inspired artificial cilia could help move drugs to a target

Like the tiny organelles used to propel some bacteria, artificial cilia developed by German engineers could someday help deliver drugs.

Developer of unique delivery technology for eye care expanding in Europe

Oraya Therapeutics, the developer of a low energy X-ray beam that can safely deliver radiation therapy to the into the eye, is expanding its presence in Europe. The 20-minute one-time procedure is designed to reduce the need for anti-vascular endothelial growth factor injections in patients with wet age-related macular degeneration.

Nanoparticles deliver agents to spur immune system into action against cancer

Researchers have found a way to use nanoparticles to deliver drugs that can "wake up" the immune system and fortify its natural response to harmful cancer cells in the body.

Amid fears of antibiotics shortage, DNA origami technique developed to combat E. coli, other bugs

Researchers at the National University of Singapore have developed a method for delivering the polypeptide antibiotic actinomycin D with modified, self-assembled DNA nanopyramid against bacteria such as E. coli and Staphylococcus aureus, the bug causes staph infections.

AcelRx discusses sublingual painkiller's rejection with concerned investors

On the heels of FDA's rejection of the AcelRx New Drug Application for sublingually delivered postoperative pain killer Zalviso, CEO Richard King expounded on the "optical system errors" of the opioid drug's handheld, preprogrammed delivery device during a July 28 conference call with investors.  

Mannkind's inhaled insulin still needs marketing partner

Mannkind endured a grueling 10-year battle for FDA approval of its inhaled insulin drug/device combination product, Afrezza. Now the dillema is how to sell it. The company needs to find a marketing partner fast. 

Most absorbent material on Earth gives poorly soluble drugs a boost

A record-breaking material discovered last year by Swedish researchers has passed another milestone for drug delivery, showing it can hold poorly soluble drugs and, down the road, deliver them with a fast dissolution rate.

MIT engineers discover key mechanism behind gold nanoparticle delivery

Gold nanoparticles are once again in the drug delivery spotlight as MIT scientists have discovered a mechanism by which the particles enter cells and could thus act as better drug carriers.