Israeli subcutaneous delivery company NeuroDerm is forging ahead with its Parkinson's patch, enrolling patients in its second Phase II clinical trial of its patch pump designed to treat the disease with steady concentrations of the tried-and-true drug levodopa.
The Michael J. Fox Foundation for Parkinson's Research is giving money to Ezose Sciences in New Jersey to look at the role that glycans play in Parkinson's disease.
Canada-based Cynapsus has come up with the first sublingual option for the delivery of apomorphine to patients with Parkinson's disease to control their debilitating "off" episodes. This week, the company heralded results from a study comparing the thin film strip with a subcutaneous injection of the same drug, noting a reduction in side effects.
Prothena's PRX002, a preclinical treatment targeting Parkinson's disease, is at the heart of a deal with Swiss pharma giant Roche, worth up to $600 million plus 30% of U.S. profits to the Irish biotech.
A new study out of UCLA points to a potential biomarker for identifying which patients have the "fast" form of the disease and will need significant help early on.
Spotting early-stage Parkinson's disease is a major goal, because it could be key to developing treatments that stop, or at least slow its progression. But where can you reliably find the best biomarker to accomplish this? It might be just under the skin, researchers from Beth Israel Deaconess Medical Center have concluded.
Parkinson's disease is bad enough, but when it also involves dementia the condition is particularly difficult. A recent study published online in PLoS ONE suggests that lipids involved in ceramide metabolism may serve as a biomarker for people with Parkinson's who are at increased risk for mild cognitive impairment.
Civitas Therapeutics picked up $38 million in second-round financing to finish a Phase IIb trial and begin Phase III for its ARCUS respiratory delivery platform to treat Parkinson's disease.
The degree of neuroinflammation was significantly associated with more severe depression, fatigue and cognitive impairment even after taking into consideration other factors, such as age, gender and disease duration.
A research team has developed a Parkinson's biomarker diagnostic test that is showing promise on its own and fueling momentum in a broader effort to tackle the disease and figure out what makes it tick.