Research in drug delivery is shifting further and further to the nano scale, and while nanotechnology still hovers for the most part just short of the clinical stage, new techniques in manufacturing the particles are crucial to bringing them to the next step.
To tackle difficult-to-treat drug-resistant ovarian cancer, researchers at Tel Aviv University have developed nanoparticles designed to accumulate in clusters in tumors to deliver chemotherapy, increasing efficacy and reducing side effects.
Researchers at UCLA's Jonsson Comprehensive Cancer Center have developed a light-activated delivery system for chemotherapy.
Alternatives means of delivering drugs such as paclitaxel could have a similar effect to drug-eluting stents without the invasive procedure, according to a new study to be published in the journal Nanomedicine: Nanotechnology, Biology and Medicine.
Using one of nature's simplest structures--the diamond--researchers at UCLA have developed a nanogel that can be embedded into contact lenses, with the ultimate goal of delivering glaucoma drugs to the eye over an extended period of time.
Researchers in China published an article in the journal Biomedical Materials demonstrating the drug-delivery potential of new gold nanoshells for cancer that also use hyperthermic effects to bring toxic cancer drugs to tumors with fewer side effects.
Scientists from Alnylam teamed with MIT researchers to develop a new nanoparticle platform with which to better deliver the genetic material to the liver. With MIT professor Robert Langer as one of its authors, the team published a paper in the journal Proceedings of the National Academy of Sciences highlighting its particles, which are inspired by the vehicles the body uses to transport cholesterol.
Patients with muscular dystrophy suffer from the dysfunction of the gene that produces dystrophin, which is a protein that maintains muscle cells' performance. And a team of researchers from Washington University School of Medicine in St. Louis has found that another factor might also play a role in the weakened muscles: The cells aren't properly recycling their waste.
San Diego drug delivery company Sonrgy snagged exclusive rights to an ultrasound-based nanotech delivery platform conceived at the University of California, San Diego.
MIT professor and entrepreneur Robert Langer is behind another innovative nanotechnology application for drug delivery, this time helping develop a model that could help researchers understand the way nanoparticles penetrate blood vessel walls.