Gold nanoparticles are once again in the drug delivery spotlight as MIT scientists have discovered a mechanism by which the particles enter cells and could thus act as better drug carriers.
Patients with pancreatic cancer whose disease still persists after regular treatments may benefit from a new cancer drug nanoliposome formulation, according to a presentation at the European Society for Molecular Oncology's 16th World Congress on Gastrointestinal Cancer.
Researchers at the University of Pennsylvania said they have uncovered a delivery method to treat acute pulmonary inflammation, a condition that afflicts patients suffering from multiple blood transfusions, sepsis, lung surgery and acute lung trauma and has a mortality rate as high as 40%.
Researchers at the University of Georgia have developed a new formulation of the chemotherapy drug cisplatin that targets mitochondrial DNA, and is delivered via a polymeric nanoparticle 1,000 times smaller than the width of human hair.
Researchers in Boston have developed new drug-delivering nanoparticles that could target and kill bone cancer cells by homing in on calcium. Besides showing in mouse models to slow myeloma growth and prolonging survival, the treatment also enhanced bone strength and volume.
MicroLin Bio, a developer of microRNA treatments for cancer, is expected to price its $30 million IPO on the Nasdaq this week. Delays and share dilution have taken some of the shine off the event, but investors enthiusiam will ultimately hinge on the fate of its proprietary nanoparticle delivery technology.
The FDA on June 24 issued three final guidances and a draft guidance for industry to clarify the use of nanotechnology in FDA-regulated products, a decision that will affect the drug delivery arena as it becomes more dependent on nano-engineerin g.
Harvard University researchers have developed a system for releasing high doses of drugs in short bursts using ultrasound and self-healing hydrogel. Future therapy could therefore be highly customized and locally delivered at specific times, as opposed to the dominant sustained release paradigm.
Researchers at UC Santa Barbara have concocted a new type of silver nanoparticle designed to deliver cancer drugs that can also dissolve and become inactive if it doesn't reach the tumor. The innovation solves some safety issues associated with nanotechnology and reduces side effects from the cancer drugs themselves, the scientists say.
Researchers in Singapore have developed a nanotech solution that could provide months of treatment in a single application.